AEIOUThe Entrepreneurial Core
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Early Enrollment: 25% Savings ends November 12.
Next cohort begins January 15 · $500 deposit reserves your seat.
Reserve your seat →
The Entrepreneurial Core

Raise capital.Run the board.Control the exit.

Strategic & Tactical Training, Founding to Exit

Online executive education for working professionals: short on-demand lessons, reading and exercises, with a live Zoom class every two weeks. Graduates earn the Executive Certificate in Entrepreneurial Leadership.

A participant working through a lesson on her laptop
How it works

Online executive education, built around your work week.

01
On-demand lessons
Short video lessons, reading and reinforcement exercises. Work through them on your own schedule, from anywhere.
02
Live Zoom class every two weeks
Your cohort meets online with the instructors to apply the material to real companies and real deals.
03
About 3 to 5 hours a week
Built for working professionals. No campus and no travel required.
Internationally Recognized Instructors
The Wall Street Journal — AEIOU and Chris Velis coverage
Wall Street Journal
LSI Emerging MedTech Summit — Keynote Speaker
LSI Summit
CNBC Disruptor 50 — Auris Health (2020)
CNBC Disruptor 50
ACG New York Champion’s Award Winner
ACG Champion’s Award
MedTech Breakthrough Award
MedTech Breakthrough
Tested and Delivered Globally
Chris Velis delivering the keynote at the Chengdu Global Innovation & Entrepreneurship Fair, China
Chris Velis mentoring and judging the Harvard President’s Innovation Challenge at Harvard Innovation Labs
Chris Velis receiving recognition at UAE Innovation Week as keynote speaker for the Dubai government and Ministry of Health
Dr. Christos Kelepouris at the Acropolis, Athens, Greece
Dr. Christos Kelepouris leading international executive education in China
Dr. Christos Kelepouris teaching executive education at the U.S. Embassy in Tunisia
Chris Velis speaking to the U.S. Defense Health Agency and Walter Reed National Military Medical Center
Chris Velis on a MedTech / Biotech panel at the Wyss Institute, Harvard University, Boston
Chris Velis at the SSII Robotics public uplisting ceremony at NASDAQ
AEIOU team in Asia with Dr. Christos Kelepouris
Chris Velis meeting with Mubadala, the Abu Dhabi sovereign wealth fund, in San Francisco
Chris Velis with Bob McDonald, former Chairman and CEO of Procter & Gamble, discussing innovation
Who it is for

You are in the right place if you want…

01The structural mechanics of building, financing, governing and exiting a company, learned before the stakes are highest
02Governance that works for the company and for the founder
03Negotiation skills that level the field against repeat players with greater resources
04The resilience that elite-level entrepreneurship requires, trained rather than assumed
05Training that no business school provides, whether you went to one or not
06Access to operators who have been at the table as bankers, investors and founders when billions were at stake
The framework

Two risks. One you know. One you will learn.

The risk you expect
Elephant Risk

The product-to-market challenge every entrepreneur signs up for. Building something people want and delivering it at scale. This is the risk that should define the journey.

Inherent to the venture. Cannot be eliminated.
vs
The risk you can learn to manage
Structural Risk

The deals, governance and architecture that decide who keeps the value a company creates. Signed, negotiated and locked in early, long before an exit.

Capital architectureBoard compositionInvestor negotiationsContractsRegulatoryIP & patentsLicensingLawsuitsExit mechanics
Preventable. Trainable. Manageable.

We train founders in the second risk, so the only exposure left is the risk you chose to take. Luck, hype and hidden terms give way to clarity, control and structural competence.

The program

Eight modules. One structural operating system.

Delivered online and built around a working schedule: short on-demand video lessons, reading and reinforcement exercises, and a live Zoom class with the instructors every two weeks. You apply the templates, frameworks and case studies to your own company. Completing the program leads to the Executive Certificate in Entrepreneurial Leadership.

MODULE 01
Unbreakable
The Resilient Entrepreneurial Mindset
Founders who last build resilience into a system rather than relying on adrenaline and hope.
Read the full description →
MODULE 02
Branding
Building Authority Through Story
Building faith, trust and confidence, systematically, until the market recognizes your company as credible, consistent and competent.
Read the full description →
MODULE 03
Capital & Value
Funding Pathways & Deal Mechanics
Every capital decision you make today shapes what happens at exit. Valuations, terms, preferences and governance provisions compound.
Read the full description →
MODULE 04
Negotiation
High-Stakes Deals & Everyday Power
Design leverage, manage cognitive traps, and control the narrative in every deal that determines your outcome.
Read the full description →
MODULE 05
Boards & Governance
Power, Duties, and Control
How boards really work, what the documents allow, and how to keep governance working for the company and its founders.
Read the full description →
MODULE 06
Expansion
The Architecture of Scale
The systems, culture and leadership that take you from 1 to 10 will not carry you from 10 to 100. Expansion is transformation, not addition.
Read the full description →
MODULE 07
Exit Strategy
Liquidity and Legacy
How exit structure, timing and stakeholder alignment determine whether founders capture the value they created.
Read the full description →
MODULE 08
AI for Business
Turning AI Capability Into Business Leverage
Take one real AI opportunity and test it: what changed, what else must change, whether the evidence and economics hold, and who keeps the value. You finish with a defensible decision to proceed, modify, or stop.
Read the full description →
Next cohort begins January 15, 2027.
Tuition & enrollment →
Your path forward

Choose your track.

Individuals · Teams · Advisors
For Entrepreneurs

The eight-module structural operating system covering cap tables, governance, negotiation and exits. For individuals, teams and advisors who want to understand what they are signing and keep the value they create.

See tuition →
Venture & private equity funds
For Equity Investors

Enroll your portfolio founders in the same eight-module online program, taught by the same operators. When your founders understand the structure, they protect their outcome and yours.

Talk to us →
Physicians · Clinician-innovators · Hospitals
For Healthcare Innovators

Structural literacy plus clinical translation: IP, regulatory pathways, reimbursement, compliance and exit mechanics, built for physician-entrepreneurs.

Visit AEIOU Medical →
Built by operators. For founders.

Meet your instructors.

Christopher J. Velis, NACD.DC
Christopher J. Velis, NACD.DC
Serial Founder · Board Director · Venture Investor · Lead Inventor

Founded Auris Health, leading to a $5.75 billion exit to Johnson & Johnson, the largest acquisition of a venture-backed medical device company on record.

Full credentials →
Dr. Christos Kelepouris
Dr. Christos Kelepouris
DBA · JD · Fulbright Specialist · UAE–Stanford Innovation Fellow

Selected by the UAE Prime Minister’s Office as a Stanford Innovation Fellow. 15+ years developing founders and advising across four continents.

Full credentials →
What leaders say
“Exactly what the startup world has been missing.”
Long before AEIOU Academy existed, Chris helped me navigate the complexity of building and scaling companies with clarity, discipline, and a level of rigor that protects founders from moving blindly or in the dark.
Stuart Koslick, P.Eng., MAScStuart Koslick, P.Eng., MASc
CEO, Tomoverse Imaging · Professor of Practice, Department of Surgery, McGill University
“I won because of what he taught me.”
When I was facing a critical license negotiation and a turbulent funding round, his AEIOU guidance gave me the clarity and decision structure to break chaos into solvable moves.
Michael McCurdy M.D.Michael McCurdy M.D.
Clinical Professor, University of Maryland · Founder, Sima Biomedical, Inc.
“This program stands out immediately.”
In my career evaluating training and leadership programs across the U.S. Army and beyond, very few met the level of rigor, structure, and real-world execution I see in AEIOU.
Dr. Tamas HorvathDr. Tamas Horvath
Bronze Star Recipient · Former Chief Quality Assurance & Accreditation Officer, United States Army
“Rare, highly practical, and essential.”
Dr. Christos' advisory work builds disciplined judgment around risk long before it appears on a balance sheet, when it is still preventable. That capability is essential at the senior banking and board level.
Fatma AlShehhiFatma AlShehhi
Senior Credit Officer, National Bank of Ras Al Khaimah, UAE
“A successful exit.”
Utilizing what I learned as a guide, the company I founded had a successful exit. The fundamental knowledge Chris provided was instrumental in navigating challenging Board matters, building consensus, and ensuring a successful outcome for all.
Mark JohansonMark Johanson
CEO, Scandius, Inc.
“A map for entrepreneurs.”
AEIOU gives entrepreneurs what I try to give students: visibility into the stages, decisions, and controls before the stakes are real. I came as a founder curious whether structural judgment could really be taught. It can, and the framework holds across industries and across borders.
Alina He 贺玉肖Alina He 贺玉肖
Founder, IvyStart Education · International Education Consultant
The evidence

Why structure deserves its own education.

56% → 36% → 23%

Median founder ownership after priced seed, Series A and Series B. Each round, the structure takes more than the market does.

Carta Founder Ownership Report, 2020–2024
~75%

Venture-backed companies that never return investor capital. Even companies that build working products can lose everything to deal structure.

Shikhar Ghosh, Harvard Business School
81%

Founders who believed their chances of success exceeded 70%. The same confidence that builds companies makes structural danger hard to see.

Cooper, Woo & Dunkelberg, Journal of Business Venturing, 1988
The Entrepreneurial Leadership Readiness Score

See your strengths, and where to grow.

A free self-assessment across the seven domains of entrepreneurial leadership. You receive a personal report showing where you are strong, where to focus, and which parts of the program would do the most for you. About 18–22 minutes. Scoring is automatic, and we review every report before we send it, so it arrives by email within a few days. Your responses are confidential.

What you get and how it works →
  1. 01Founder Psychology
  2. 02Brand Authority
  3. 03Capital Architecture
  4. 04Negotiation
  5. 05Governance
  6. 06Systems for Scale
  7. 07Exit Orchestration
The next cohort

More than a credential. A community of builders.

A global community of structurally literate entrepreneurs who negotiate better, govern better and keep the value they create. The next cohort begins January 15, 2027.

Reserve your seatGet your Entrepreneurial Leadership Readiness Score first →
Early Enrollment: 25% Savings ends November 12.
Next cohort begins January 15 · $500 deposit reserves your seat.
Reserve your seat